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KMID : 0377619920570070427
Korean Jungang Medical Journal
1992 Volume.57 No. 7 p.427 ~ p.430
Effects of Cepharanthine on the Peripheral Blood During AnticancerChemotherapy for Patients with Gastric and Colorectal Cancer



Abstract
After curative resection of advanced gastric and colorectal cancer, we have done the adjuvant therapy with 5FU, mitomycin and OK432 for 14 cases of gastric cancer and Nidran and UFT for 12 cases of colorectal cancer. During these adjuvant chemotherapy and radiation therapy, we prescribed cepharanthine 6 mg everyday more than four weeks. Cepharanthine recovered the leukopenia in 9 cases (56.3 %) among 16 cases whose leukocytes were less than 3,000/mm3. Cepharanthine had no effect on hemoglobin, hematocrit, number of platelet, liver function and renal function.
The cepharanthine was the effective and nontoxic agent for the leukopenic patients during adjuvant chemotherapy and radiotherapy.
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